<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">MRP</journal-id><journal-title-group><journal-title>Medical Research and Practice</journal-title></journal-title-group><issn>2993-9690</issn><eissn>2993-9704</eissn><publisher><publisher-name>Art and Technology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/mrp.2258</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>伴水疱的色素性痒疹一例</title><url>https://artdesignp.com/journal/MRP/1/3/10.61369/mrp.2258</url><author>孙明慧,朱晓芳</author><pub-date pub-type="publication-year"><year>2023</year></pub-date><volume>1</volume><issue>3</issue><history><date date-type="pub"><published-time>2023-10-20</published-time></date></history><abstract>报告伴水疱的色素性痒疹1例。患者女，45岁，主诉背部及胸腹部皮疹伴瘙痒6月余。皮肤科检查：背部及胸腹部可见红斑及红褐色丘疹，部分融合成片，部分区域可见密集小水疱，疱液澄清，尼氏征阴性。背部皮损组织病理检查：表皮内多房水疱形成，疱液内可见嗜酸性粒细胞、淋巴细胞和中性粒细胞浸润，基底细胞空泡化变性，真皮浅层血管扩张，周围可见淋巴细胞及少许嗜酸性粒细胞浸润，真皮内可见嗜色素细胞。临床诊断为色素性痒疹。门诊予多西环素100mg，每日2次口服，治疗2周后瘙痒消失，红斑水疱消退，伴有色素沉着。</abstract><keywords>色素性痒疹，水疱，多西环素</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1]Nagashima M, Ohshiro A, Shimizu N. A peculiar pruriginous dermatosis with gross reticular pigmentation[J]. Jpn J Dermatol.1971,81:38&amp;ndash;9.[2] 王金容，王丽芬，叶建州，等．伴有水疱的色素性痒疹1 例［J］．临床皮肤科杂志，2019,48(3):172-174.[3] 刘佳玮，马东来．色素性痒疹临床表现及组织病理学分析［J］．中国美容医学，2015,24(18):41-43.[4] 孙德飞，孙昂远，张婷婷，等．色素性痒疹3 例并文献复习［J］．中国中西医结合皮肤性病学杂志，2021,20(1):74-76.[5]Beutler B D , Cohen P R , Lee R A . Prurigo Pigmentosa: Literature Review.[J]. Am J Clin Dermatol, 2015, 16(6):533-543.[6]Houriet C, Perruchoud DL, Beltraminelli H, et al.Prurigo Pigmentosa in White Monozygotic Twins[J]. JAMA Dermatology, 2017, 153(3):353-354.[7]Lu LY, Chen CB. Keto Rash: Ketoacidosis-Induced Prurigo Pigmentosa[J]. Mayo Clin Proc. 2022,97(1):20-21.[8]Aerts O, Dendooven E, Siozopoulou V. Dieting Resulting in Prurigo Pigmentosa (&amp;ldquo;Keto Rash&amp;rdquo;)[J]. J Allergy Clin Immunol Pract. 2021,9(11):4149-4150.[9]Yamada D, Fujikawa T. Prurigo Pigmentosa[J]. Am J Med. 2018,131(1):e11-e12.[10]Satter E , Rozelle C , Sperling L . Prurigo Pigmentosa: An under ‐recognized inflammatory dermatosis characterized by an evolution of distinctive clinicopathological features[J]. J Cutan Pathol, 2016, 43(10):809-814.[11] 何婷婷，陈忠业，王丽金，等．自愈性色素性痒疹一例［J］．中国麻风皮肤病杂志，2019,35(6):358-359.[12] 曹燕，王林，贾虹，等．米诺环素在皮肤科临床中的应用［J］．实用皮肤病学杂志，2016,9(2):120-123.[13]Jang M S , Suh K S , Kwon D I , et al. Successful treatment with narrowband ultraviolet B phototherapy in prurigo pigmentosa[J]. J Eur Acad Dermatol Venereol,2021,35(11):e796-e798.[14]Ross A, Dunn R, Bekhor P, et al. Prurigo pigmentosa - Response to treatment with Q-Switched neodymium: YAG at 532 nm[J]. Australas J Dermatol. 2019,60(2):147-149.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
