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<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">MRP</journal-id><journal-title-group><journal-title>Medical Research and Practice</journal-title></journal-title-group><issn>2993-9690</issn><eissn>2993-9704</eissn><publisher><publisher-name>Art and Technology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/MRP.2026050036</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>基于320排宽探测器CT的冠状动脉CT血管成像“双低”扫描策略综述</title><url>https://artdesignp.com/journal/MRP/4/5/10.61369/MRP.2026050036</url><author>陈静,龚金山</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>4</volume><issue>5</issue><history><date date-type="pub"><published-time>2026-05-20</published-time></date></history><abstract>冠状动脉CT血管成像（CCTA）目前已成为冠心病无创诊断和筛查的常用手段，不过在实际应用中，辐射对人体的影响以及碘对比剂可能带来的肾损伤问题仍需重点关注。320排宽探测器CT（WDCT）借助其16厘米Z轴方向等体素覆盖能力，为从源头降低CCTA检查中的辐射剂量和对比剂使用量提供了技术支持。本文系统梳理了其技术原理、个性化操作、临床验证及问题，重点分析单心动周期采集、前瞻性心电门控容积扫描与低管电压的联合应用，数据显示，通过调整优化扫描方案，有效辐射剂量稳定控制在1 mSv 以内，对比剂用量也可减少到30 mL以下，同时不会影响诊断所需的图像质量。未来光子计数技术与宽探测器结构的结合、标准化且个性化方案的确立、基于风险评估的综合模型构建等方向，将在未来推动&amp;ldquo;双低&amp;rdquo;CCTA检查朝着更安全、更精准的方向进步。</abstract><keywords>冠状动脉CT 血管成像,320排CT,宽探测器CT,辐射剂量,对比剂用量,个性化扫描,深度学习重建</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1] Sabarudin A, Sun Z, Ng K-H.Coronary computed tomography angiography with prospective electrocardiography triggering: a systematic review of image quality and radiation dose [J]. Singapore Medical Journal, 54(1):15-23, 2013.[2] Pan Y, Jia C-F.The research advancements on the advantages and limitations of coronary computed tomography angiography at low tube voltage: a literature review [J]. Quantitative Imaging in Medicine and Surgery, 15(6):5859-5867, 2025.[3] Fan Y, Qin T, Sun Q, et al.A review of factors affecting radiation dose and image quality in coronary CTA performed with wide-detector CT [J]. Tomography, 10(11):1730-1743, 2024.[4] Huang L, Zhao F, Zhong Z, et al.Optimizing coronary computed tomography angiography image quality with motion-compensated reconstruction: a prospective electrocardiogram-triggered mode with second-generation dual-layer spectral detector computed tomography [J]. Journal of Thoracic Disease, 17(10):8196-8209, 2025.[5] Vargas E E, Tetteroo P M, Kristiansen C H, et al.Optimizing coronary CT angiography with spectral dual-layer CT: motion-compensated virtual monoenergetic imaging achieves 50% contrast dose reduction in a phantom study [J]. International Journal of Cardiovascular Imaging, 2025.[6] Yuan D, Wang L, Lyu P, et al.Evaluation of image quality on low contrast media with deep learning image reconstruction algorithm in prospective ECG-triggering coronary CT angiography [J]. International Journal of Cardiovascular Imaging, 40(6):1377-1388, 2024[7] Wang Z, Chen G, Song D, et al.Reduced contrast agent volume using a heart-rate dependent and free-breathing scanning protocol in coronary computed tomography angiography (CTA) for patients with chronic obstructive pulmonary disease (COPD) [J]. Bmc Cardiovascular Disorders, 25(1), 2025.[8] Zou L-M, Xu C, Xu M, et al.Improved image quality and diagnostic performance of coronary computed tomography angiography-derived fractional flow reserve with super-resolution deep learning reconstruction [J]. Quantitative Imaging in Medicine and Surgery, 15(9), 2025.[9] Zhang Q, Sheng A Z, Ren H, et al.Tripartite strategy for dual reduction of radiation and iodine dose in obese CCTA: high-iodine contrast, 80 kVp, and deep learning reconstruction [J]. Medicine, 104(44), 2025.[10] Ronning M, Johansen E, Rusandu A.Photon-counting CT versus energy-integrating detectors for cardiac imaging: a systematic review of evidence from in vivo human studies on image quality and radiation dose [J]. Bmc Medical Imaging, 25(1), 2025.[11] Xu C, Sun Y, Wang L, et al.Spectral photon-counting detector coronary CTA with reduced radiation and contrast medium dose in inflammation-associated coronary artery disease: A prospective study [J]. American Journal of Roentgenology, 225(6), 2025.[12] Tremamunno G, Pinos D, Zsarnoczay E, et al.Influence of virtual monoenergetic reconstructions on coronary CT angiography-based fractional flow reserve with photoncounting detector CT: intra-individual comparison with energy-integrating detector CT [J]. Insights into Imaging, 16(1), 2025.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
