<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">ME</journal-id><journal-title-group><journal-title>Modern Engineering</journal-title></journal-title-group><issn>2996-6973</issn><eissn>2996-6981</eissn><publisher><publisher-name>Art and Technology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/ME.2026020028</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>基于Ti3C2/Au自组装构建电化学适配体传感器检测四环素</title><url>https://artdesignp.com/journal/ME/3/2/10.61369/ME.2026020028</url><author>王格,张琰,刘洁</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>3</volume><issue>2</issue><history><date date-type="pub"><published-time>2026-02-20</published-time></date></history><abstract>四环素类抗生素滥用严重威胁食品安全与人体健康，研发快速灵敏的检测技术，是防控残留危害的重要保障。本研究创新性构建适配体功能化Ti3C2/Au纳米复合材料电化学传感器，结合Ti3C2高导电性、Au优良生物相容性与适配体高特异性识别机制，实现TET超灵敏检测。该传感器线性检测范围1&amp;ndash;40 ng/mL，检测限低至4.8017 ng/mL，选择性、抗干扰性与重现性优异，牛奶实际样品加标回收率101.33%&amp;ndash;103.36%，结果准确可靠，在食品安全快速检测领域应用前景广阔，为动物性食品抗生素残留监测提供高效便捷新策略。</abstract><keywords>MXene,纳米材料,适配体传感器</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1]Gao X, Sun Z, Wang X, et al. Construction of a ratiometric electrochemical aptasensor based on graphdiyne-methylene blue and Fc-labeled hairpin for cyclic signal amplification detection of kanamycin[J]. Sensors and Actuators B: Chemical, 2022, 373: 132706.[2]Li H, Geng W, Haruna S A, et al. A target-responsive release SERS sensor for sensitive detection of tetracycline using aptamer-gated HP-UiO-66-NH2 nanochannel strategy[J]. Analytica Chimica Acta, 2022: 339999.[3]Wu D, Wu M, Yang J, et al. Delaminated Ti3C2Tx (MXene) for electrochemical carbendazim sensing[J]. Materials Letters, 2019, 236: 412-415.[4]Keneshbekova A, Smagulova G, Kaidar B, et al. MXene/carbon nanocomposites for water treatment[J]. Membranes, 2024, 14(9): 184.[5]Su H Y, Sun K, Gu X K, et al. Finding key factors for efficient water and methanol activation at metals, oxides, MXenes, and metal/oxide interfaces[J]. ACS catalysis, 2022, 12(2): 1237-1246.[6]Chen R, Pang W, Li S, et al. Recent advances and prospects in MOF/MXene sensors[J]. Sustainable Materials and Technologies, 2024, 40: e00935.[7]Labib M, Sargent E H, Kelley S O. Electrochemical methods for the analysis of clinically relevant biomolecules[J]. Chemical reviews, 2016, 116(16): 9001-9090.[8]Wang W, Gunasekaran S. MXene/Gold nanoparticles heterostructure as catalase mimic for colorimetric detection of penicillin G[J]. Chemical Engineering Journal, 2024, 482: 148693.[9]Wang W, Yin Y, Gunasekaran S. Gold nanoparticles-doped MXene heterostructure for ultrasensitive electrochemical detection of fumonisin B1 and ampicillin[J]. Microchimica Acta, 2024, 191(5): 294.[10]Du X, Du W, Sun J, et al. Self-powered photoelectrochemical sensor for chlorpyrifos detection in fruit and vegetables based on metal&amp;ndash;ligand charge transfer effect by Ti3C2 based Schottky junction[J]. Food Chemistry, 2022, 385: 132731.[11]Nguyen D K, Jang C H. Label-free liquid crystal-based biosensor for detection of dopamine using DNA aptamer as a recognition probe[J]. Analytical Biochemistry, 2020, 605: 113807.[12]Zhu C, Liu D, Li Y, et al. Hairpin DNA assisted dual-ratiometric electrochemical aptasensor with high reliability and anti-interference ability for simultaneous detection of aflatoxin B1 and ochratoxin A[J]. Biosensors and Bioelectronics, 2021, 174: 112654.[13]Zheng J, Wang B, Ding A, et al. Synthesis of MXene/DNA/Pd/Pt nanocomposite for sensitive detection of dopamine[J]. Journal of Electroanalytical Chemistry, 2018, 816: 189-194.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
