<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">CDCST</journal-id><journal-title-group><journal-title>China Daily Chemical Science Technology</journal-title></journal-title-group><issn>2997-7096</issn><eissn>2997-710X</eissn><publisher><publisher-name>Art and Technology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/CDCST.7984</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>羟基磺基甜菜碱表面活性剂与DNA相互作用研究</title><url>https://artdesignp.com/journal/CDCST/1/2/10.61369/CDCST.7984</url><author>王子涵,段泽峰,朱海林,张婷婷,胡志勇,孙永强</author><pub-date pub-type="publication-year"><year>2024</year></pub-date><volume>1</volume><issue>2</issue><history><date date-type="pub"><published-time>2024-11-25</published-time></date></history><abstract>采用电导率、紫外光谱、粒度分析、Zeta电位以及荧光光谱等方法研究两种羟基磺基甜菜碱两性表面活性剂（HSB-12、HSB-14）与DNA的相互作用。结果表明：HSB-12/DNA体系和HSB-14/DNA体系的等电点范围为6~9；随着NaBr浓度增加，表面活性剂/DNA体系的透过率增加，粒径减小，微极性减小；与pH=8相比，pH=5时表面活性剂/DNA体系的透过率更高，粒径更小。</abstract><keywords>羟基磺基甜菜碱表面活性剂 ,DNA ,等电点 ,相互作用</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1] 刘惠中．DNA参与阴/阳离子表面活性剂的聚集行为、聚集体结构与性能研究[D]. 博士学位论文．青岛：山东大学，2020[2] 王万霞．偶联表面活性剂及其与DNA相互作用研究[D]. 硕士学位论文．上海： 华东理工大学，2010[3] Mel&amp;rsquo;nikova S M, Sergeyev V G, Yoshikawa K. Discriete coilglobule transition of large DNA induced by cations surfantant [J].Chemical. Society, 1995, 117(9): 2401-2408[4] Mel&amp;rsquo;nikova S M, Sergeyev V G, Yoshikawa K. Transition of double-stranded DNA chains between random coil and compact globule states induced by cooperative binding of cationic surfactant [J].Chemical.Society., 1995, 117(40): 9951-9956[5] Z h u D . M . , E v a n s R . K . . M o l e c u l a r M e c h a n i s m a n d Thermodynamics Study of Plasmid DNA and Cationic Surfactants Interactions [J]. Langmuir, 2006, 22(2): 3735-3743[6] 邹明静，董懿萱，穆昀，等．鲑鱼精DNA-阳离子表面活性剂体系的共振光散射光谱分析及应用 [J]. 当代化工，2023, 52(4):771-774[7] 朱海林，胡志勇，王建龙，曹端林．系列羟基磺基甜菜碱表面活性剂的合成及胶束化行为研究．日用化学工业，2012, 42(6):405-409[8] Xiaofang Zhao, Yazhuo Shang, Honglai Liu. Complexation of DNA with cationic gemini surfactant in aqueous solution [J]. J. Colloid Interface Science, 2007, 314: 478-483.[9] Wang Y L, Dubin P L, Zhang H W. Interaction of DNA with catinic micelles:effects of micelle surface charge density,micelle shape,and ionic strength on complexatuin and DNA collapse [J]. Langmuir, 2001,17(5): 1670-1673.[10] R. Zana, M. In, H. Levy, G. Duportail. Alkanediyl-&amp;alpha;,&amp;omega;-bis (dimethylalkylammonium bromide). 7. Fluorescence probing studies of micelle micropolarity and microviscosity[J]. Langmuir, 1997, 12:5552-5557.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
