<?xml version="1.1" encoding="utf-8"?>
<article xsi:noNamespaceSchemaLocation="http://jats.nlm.nih.gov/publishing/1.1/xsd/JATS-journalpublishing1-mathml3.xsd" dtd-version="1.1" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"><front><journal-meta><journal-id journal-id-type="publisher-id">CDCST</journal-id><journal-title-group><journal-title>China Daily Chemical Science Technology</journal-title></journal-title-group><issn>2997-7096</issn><eissn>2997-710X</eissn><publisher><publisher-name>Art and Technology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.61369/CDCST.2026020021</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title>费菜中可用于化妆品开发活性物质提取工艺及功效研究现状</title><url>https://artdesignp.com/journal/CDCST/3/2/10.61369/CDCST.2026020021</url><author>邵佳华,林紫依,任河天,廖传杰,王昌涛</author><pub-date pub-type="publication-year"><year>2026</year></pub-date><volume>3</volume><issue>2</issue><history><date date-type="pub"><published-time>2026-06-25</published-time></date></history><abstract>费菜栽培历史悠久、在中国分布广泛，是传统药用植物。近年来，费菜中活性物质的提取与鉴定已成为研究热点。费菜中黄酮类化合物、多酚及多糖含量丰富且性质稳定，具有优良的抗氧化活性，在食品保鲜领域应用广泛，同时在化妆品行业具备潜在应用价值。文章系统梳理了费菜中黄酮类化合物、多酚及多糖等活性成分的功效及其现有提取工艺，并对比分析各工艺的优劣特性，为拓宽费菜在化妆品领域的进一步开发与利用提供参考。</abstract><keywords>费菜,黄酮,多酚,多糖,提取工艺</keywords></article-meta></front><body/><back><ref-list><ref id="B1" content-type="article"><label>1</label><element-citation publication-type="journal"><p>[1]谭波,何席呈,李婷, 等.景天三七化学成分及药理作用研究进展[J]. 中国民族民间医药,2018,27(17):49-52.[2]国家中医药管理局《中华本草》编委会.中华本草( 第3册)[M]．上海: 上海科学技术出版社，1999:765-766.[3]Lee, J.,Kim, M.,Son, H.,et al. Phytochemical Characterizationand Bioactivity Evaluation of Extracts Obtained via Ultrasound-AssistedExtraction of Medicinal Plant Phedimus aizoon[J]. Plants,2024(13):1915.[4]刘亚虓,李昕卓,唐家美, 等.景天三七化学成分及药理作用研究进展[J]. 陕西中医药大学学报,2024,47(03):21-33.[5]覃柳兰,庄映红,邹虎成, 等.救心菜的研究进展及开发利用[J].长江蔬菜,2022(04):44-48.[6]熊燕,杜彩霞,段玉书, 等.黔产景天三七的化学成分及药理活性研究[J]. 中草药,2019,50(22):5404-5410.[7]Wang, K., Ge, Q., Shao, X. et al. The Antifungal Efficacy of Flavonoidsfrom Sedum aizoon L. on Grapes[J]. Food Bioprocess Technol,2024(17): 722&amp;ndash;735.[8]Liu, J., Li, C., Ding, G.,et al. Artificial Intelligence Assisted UltrasonicExtraction of Total Flavonoids from Rosa sterilis[J]. Molecules,2021(26): 3835.[9]马娇.费菜总黄酮的分离与抗氧化活性研究[D].西南科技大学,2019.[10]刘艳杰,陈曦,张晶.景天三七的化学成分和药理作用研究进展[J]. 内蒙古中医药,2016,35(04):114.[11]蔡冬宝,施月,马娇, 等.高钙菜黄酮的分级分离各级分的抗氧化活性[J]. 食品工业科技,2019,40(05):108-113.[12]罗洁,王鸿飞,许凤, 等.费菜不同组织总黄酮抗氧化与抑菌活性的研究[J]. 天然产物研究与开发,2018,30(11):1957-1962.[13]强毅,王政军,陈克克, 等.费菜多酚含量的测定及体外抗菌活性研究[J]. 食品工业科技,2013,34(05):53-56.[14]李乔,于洋,徐昙烨, 等.费菜正丁醇部位化学成分的分离与鉴定[J]. 沈阳药科大学学报,2020,37(03):240-245.[15]Qizhi Wang, Aoxue Luo, Yijun Fan, et al.In vitro antioxidantactivity of Polysaccharide from Sedum aizoon L. extracts[J]. Journal ofMedicinal Plants Research,2011,5(30):6604-6608.[16]Wang Hongfei, Liu Fei, Xu Chao, et al. Alkali-extraction and antioxidantactivity of total flavonoid from Sedum aizoon L.[J].Transactionsof the Chinese Society of Agricultural Engineering (Transactions of theCSAE), 2012, 28(1): 317 － 321.[17]Ashraf, W., Rehman, A., Hussain, A. et al. Optimization of ExtractionProcess and Estimation of Flavonoids from Fenugreek UsingGreen Extracting Deep Eutectic Solvents Coupled with Ultrasonication[J]. Food Bioprocess Technol,2024,17(4):887-903.[18]晋丛斌.景天三七中总黄酮的提取分离及抗氧化活性研究[D].上海应用技术大学,2016.[19]Xin Qi, Xin-tong Lu, Xi-han Sun,et al. The regulatory effect oftotal flavonoids of Sedum aizoon L. on oxidative stress in type 1 diabeticmice[J]. Current Research in Food Science,2022,5:1140-1147.[20]Hongli Zhang, Feilong Hao, Zhifang Yao, et al.Efficient extractionof flavonoids from Polygonatum sibiricum using a deep eutecticsolvent as a green extraction solvent[J]. Microchemical Journal,2022,175:107168.[21]Mehmet Melikoglu.Microwave-assisted extraction: Recent advancesin optimization, synergistic approaches, and applicationsfor green chemistry[J]. Sustainable Chemistry for Climate Action,2025,7:100122.[22]Chew SK, Teoh WH, Hong SL, et al. Rutin extraction from femaleCarica papaya Linn. using ultrasound and microwave-assistedextractive methods: Optimization and extraction efficiencies[J]. Heliyon,2023,9(10):e20260.[23]Congbin Jin, Xiaocong Wei, Shuli Yang, et al. Microwave-assistedExtraction and Antioxidant Activity of Flavonoids from Sedum aizoonLeaves[J]. Food Science and Technology Research,2017,23(1):111-118.[24]T. P. Vo, N. T. U. Nguyen, V. H. Le, et al. Nguyen Optimizing Ultrasonic-Assisted and Microwave-Assisted Extraction Processes toRecover Phenolics and Flavonoids from Passion Fruit Peels[J]. ACSOmega,2023,8(37):33870-33882.[25]Kshitiz Kumar, Shivmurti Srivastav, Vijay Singh Sharanagat.Ultrasound assisted extraction (UAE) of bioactive compounds fromfruit and vegetable processing by-products: A review[J]. UltrasonicsSonochemistry,2021,70:105325.[26]周敏,马雪丹,贾凯睿, 等.超声波技术在天然产物提取方面的应用进展[J]. 化工管理,2025,(28):120-123.[27]邬方宁. 超声提取技术在现代中药中的应用[J]. 中草药,2007,38(2): 315-316.[28]刘飞,王鸿飞,林燕, 等.费菜总黄酮提取工艺的研究[J].食品工业科技,2011,32(04):252-254.[29]S&amp;aacute;nchez-Camargo A.P., Mendiola J.A., Ib&amp;aacute;&amp;ntilde;ez E., Herrero M.Supercritical Fluid Extraction[EB/OL](2014)[2026-03]. https://doi.org/10.1016B978-0-12-409547-2.10753-X.[30]Quentin Gros, Johanna Duval, Caroline West, et al. On-line supercriticalfluid extraction-supercritical fluid chromatography (SFE-SFC)at a glance: A coupling story[J]. TrAC Trends in Analytical Chemistry,2021,144:116433.[31]张兴桃,张东京,董增, 等.超临界CO2萃取景天三七总黄酮的工艺优化[J]. 宿州学院学报,2017,32(05):119-122.[32]Salla K&amp;auml;lk&amp;auml;j&amp;auml;, Katja Lappalainen, Fran&amp;ccedil;ois Delattre, et al. Currentstatus of chemical- or enzyme-assisted ultrasonic pre-treatment processesfor lignocellulosic biomass to assess industrialization progress: Areview[J]. Current Opinion in Chemical Engineering,2025,48:101124.[33]CHU Q，XIE S，WEI H，et al. Enzyme-assisted ultrason － icextraction of total flavonoids and extraction polysaccha － rides in residuefrom Abelmoschus manihot L.[J] . Ultra － sonics Sonochemistry，2024(104)：106815-106820.[34]赵青青,刘强,江思雨, 等.纤维素酶辅助超声提取景天三七黄酮工艺优化及其抗氧化活性研究[J]. 农产品加工,2025,(08):28-34.[35]Ri-Fu Yang, Lin-Lin Geng, Hai-Qin Lu, et al. Ultrasound-synergizedelectrostatic field extraction of total flavonoids from Hemerocalliscitrina baroni[J]. Ultrasonics Sonochemistry,2017,34:571-579.[36]Mobasheri, F., Khajeh, M., Ghaffari-Moghaddam, M., et al. Machinelearning optimization of microwave-assisted extraction of phenolicsand tannins from pomegranate peel[J]. Sci Rep,2025,15(1):19439.[37]Sandra Pimentel-Moral, Isabel Borr&amp;aacute;s-Linares, Jes&amp;uacute;s Lozano-S&amp;aacute;nchez, et al. Antonio Segura-Carretero,Microwave-assistedextraction for Hibiscus sabdariffa bioactive compounds[J]. Journal ofPharmaceutical and Biomedical Analysis,2018,156:313-322.[38]Wong J C J , Nillian E .Microwave ‐assisted extraction of bioactivecompounds from Sarawak Liberica sp. coffee pulp: Statistical optimizationand comparison with conventional methods[J].Food Science&amp;amp; Nutrition,11(9).[39]Ja&amp;iacute;sa O. Chaves, Leonardo M. de Souza Mesquita, Monique M.Strieder, et al. Rostagno,Eco-friendly and high-performance extractionof flavonoids from lemon peel wastes by applying ultrasound-assistedextraction and eutectic solvents[J]. Sustainable Chemistry and Pharmacy,2024,39:101558.[40]Meifei Zhu, Jiayi Bao, Pengbo Liang, et al. Fuliang Hu,Extractionof flavonoids and phenolic acids from poplar-type propolis: optimizationof maceration process, evaluation of antioxidant and antimicrobialactivities[J]. LWT,2025,233:118481.[41]陈海霞,谢笔钧.树脂法从茶叶中综合提取有效成分的研究[J].精细化工,2000,17(8):493-495.[42]Harneet Kaur Kala, Rajendra Mehta, Kamal Kumar Sen, et al.Critical analysis of research trends and issues in microwave assistedextraction of phenolics: Have we really done enough,TrAC Trendsin Analytical Chemistry[J]. TrAC Trends in Analytical Chemistry,2016,85:140-152.[43]Munish Puri, Deepika Sharma, Colin J. Barrow,Enzyme-assistedextraction of bioactives from plants[J]. Trends in Biotechnology,2012,30(1):37-44.[44]邬家燕,古金银,申利群, 等.费菜汁和渣中多糖、多酚的含量测定[J]. 壮瑶药研究,2023(01):106-108.[45]Li XJ, Guo J, Xu YP,et al. Effects of heat reflux extraction on thecontent, antioxidant, and immune activity of polyphenols and flavonoidsfrom hempseed threshing residues[J]. PLOS ONE,2025,20(5):e0322134.[46]Hu, Y., Yan, B., Chen, Z.S., et al. Recent Technologies for the Extractionand Separation of Polyphenols in Different Plants: A Review[J].Journal of Renewable Materials,2022,10(6):1471-1490.[47]周文,强毅,鲁秀兰, 等.响应面法优化费菜多酚的提取工艺研究[J]. 食品工业科技,2014,35(22):249-253.[48]王佰灵,罗伦,邱婧然, 等.景天三七总多酚提取工艺的优化及活性研究[J]. 化学研究与应用,2021,33(08):1485-1493.[49]Yuxing Chai, Yanyang Xu, Yuyan Luo, et al. Ultrasound-assisteddeep eutectic solvent extraction and AB-8 resin purificationof polyphenols from Panax ginseng leaves: Process optimization andantioxidant enhancement[J]. Separation and Purification Technology,2025,378:134680.[50]郑洁,徐婷,韩伟.天然产物中有效成分不同提取方法的研究与分析[J]. 机电信息,2017(29):1-9.[51]Guo A. J., Li X. Y., Li X. Y., et al. Optimization of ExtractionProcess and Antioxidant Mechanism of Polygonatum Odoratum Polysaccharides[J]. Journal of Hefei University of Technology,2024,47(5):678-684.[52]Ashraf, S.,Ashraf, M.Z.,Miao, B.,et al. Optimizing ExtractionMethods for Bioactive Polysaccharides from Rosa rugosa and Rosadamascena[J]. Foods,2025,14(17):3211.[53]王娜,王奇志,唐健红, 等.响应面法优化费菜多糖提取工艺研究[J]. 食品工业,2013,34(03):96-100.[54]Lubek-Nguyen, A.,Ziemich&amp;oacute;d, W.,Olech, M. Application of enzyme-Assisted Extraction for the Recovery of Natural Bioactive Compoundsfor Nutraceutical and Pharmaceutical Applications[J]. AppliedSciences-Basel,2022,12(7):3467.[55]Liang, H.,Ma, Y.,Zhao, Y.,et al. A Review on the Extraction, StructuralAnalysis, and Antitumor Mechanisms of Sanghuangporus Polysaccharides[J]. Foods,2025,14(4):707.[56]Wang, Q., Wang, N., Chen, Z. Extraction and deproteinization ofpolysaccharides from Sedum aizoon L.[J]. Advanced Materials Research,2013,864-867:460-464.[57]Jing, Y.,Yan, M.,Zhang, H.,et al. Effects of Extraction Methods onthe Physicochemical Properties and Biological Activities of Polysaccharidesfrom Polygonatum sibiricum[J]. Foods,2023,12 (11):2088.[58]Sun, J., Wang, S., Duan, J. A., et al. Eco-Friendly Processing andApplication of Food-Derived Polysaccharides: Advances in Extraction,Separation and Drying[J]. Food Reviews International,2025:1-35.[59]陈文娟.响应面优化超声辅助提取养心菜多糖的工艺研究[J].井冈山大学学报( 自然科学版),2020,41(02):48-53.[60]杨艳俊,耿水连,吉慧杰, 等.景天三七多糖超声提取工艺研究[J]. 吉林化工学院学报,2014,31(09):17-20.[61]李爱华,邹录惠,王璇, 等.金花茶组植物的活性成分及其在化妆品的开发应用前景[J]. 日用化学品科学,2026,49(02):67-74.[62]董小燕,郝春艳,卢姿妍, 等.樱桃核提取物在中草药化妆品研发中的应用[C]//山西省农业科学院现代农业研究中心.2025（第三届） 农业高标准高质量发展研讨会论文集.陕西服装工程学院,2025:281-287.[63]蔡冬宝,施月,熊双丽, 等.费菜总黄酮的抗氧化活性研究[J].保鲜与加工,2018,18(06):83-88.[64]Zhang, X., Gao, L., Li, Q., et al. Four new compounds isolatedfrom the rhizomes of Phedimus aizoon (L.) 't Hart[J]. Natural ProductResearch,2024,38(15):2658-2666.[65]LI X J, SU Q Q, XUE J W, et al. Mechanisms, structure-activityrelationships, and skin applications of natural polysaccharides in anti-aging:A review[J]. International Journal of Biological Macromolecules,2025,310: 143320.[66]HUANG R R, LI R H, QIN M H, et al. A review on anti-aging actionsof plant polysaccharides[J]. Future Foods, 2025,12:100684.[67]刘畅,成玉梁,郭亚辉, 等.芦荟多糖联合茶多酚对小鼠酒精性肝损伤的预防作用[J]. 食品工业科技,2019,40(22):300-305.[68] 黄睿. 费菜多糖的免疫活性研究[D]. 延边大学,2019.[69]贾凌云,徐昙烨,王晶, 等.费菜茎叶化学成分的分离与鉴定( Ⅱ )[J]. 沈阳药科大学学报,2014,31(09):673-676.[70]金宇婷，支德，郭永泰，等． 酚类衍生物的美白和抗氧化活性［J］． 应用化学，2019,36(11):1257-1265.[71]李乔,于洋,李明晓, 等.费菜根茎化学成分的分离与鉴定[J].中国现代中药,2020,22(03):353-357.[72]杨娟,豆佳红,孙悦龙, 等.基于网络药理学与分子对接和实验验证探讨费菜抗炎作用的分子机制[J].食品工业科技,2023,44(04):12-21.[73]Jan F. Stevens, Henk&amp;rsquo;t Hart, Elizabeth T. Elema. Annabel Bolck,-Flavonoid variation in eurasian Sedum and Sempervivum[J]. Phytochemistry,1996,41(2):503-512.[74]WENJ,ZHAO X X,ZHANG Q,et al.Study on extraction processof flavonoids from seabuckthorn by ultrasonic composite enzymemethod and their antioxidant activity and stability[J].ChinaCondiment,2025,50(9):227-234.[75]Wu, M.,Liu, P.,Wang, S.,et al. Ultrasonic Microwave-AssistedMicelle Combined with Fungal Pretreatment of Eucommia ulmoidesLeaves Significantly Improved the Extraction Efficiency of Total Flavonoidsand Gutta-Percha[J]. Foods,2021,10(10):2399.[76]Zhenkai Ge, Yongheng Zhao, Xu Ling, et al. Ultrasound-assistedAqueous Two-Phase Extraction of Flavonoids fromScutellariae Radixand Evaluation of their Bioactivities In Vitro[J]. Current AnalyticalChemistry,2024,20(2):e300124226476.</p><pub-id pub-id-type="doi"/></element-citation></ref></ref-list></back></article>
