罗马洋甘菊挥发油脂质体凝胶对特应性皮炎的治疗作用研究

CDCST

China Daily Chemical Science Technology

2997-70962997-710X

Art and Technology

10.61369/CDCST.2026010015

Article

罗马洋甘菊挥发油脂质体凝胶对特应性皮炎的治疗作用研究https://artdesignp.com/journal/CDCST/3/1/10.61369/CDCST.2026010015程军,张大存,汪春风,胡晗璐,钱雪,陈斌,陈国庆

2026

2026-03-05

本研究旨在制备白及多糖包裹的罗马洋甘菊挥发油脂质体凝胶（CNVO-LG），探究其对小鼠AD的治疗效果。结果表明，罗马洋甘菊挥发油脂质体平均粒径145.6 nm，多分散系数为0.195，大小均一；脂质体凝胶呈疏松多孔网络结构。小鼠AD模型试验表明，CNVO-LG可显著改善AD小鼠的皮肤损状态，同时有效抑制AD小鼠皮肤和血清中IgG、TNFα、IL-4以及IFNγ等细胞因子水平。综上，罗马洋甘菊挥发油脂质体凝胶在治疗AD方面展现出较大应用潜力，为AD治疗提供了潜在方案。罗马洋甘菊,挥发油,脂质体凝胶,特应性皮炎

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